A summary of published research, not medical advice. See the Disclaimer.
All 4 studies in the study browser
Included: human randomized controlled trials, systematic reviews and meta-analyses on BPC-157 indexed in PubMed, plus uncontrolled human reports, because no controlled human trials exist. A PubMed search on October 15, 2026 returned 15 records. 4 remain after excluding protocols, retractions, comments and papers that did not study BPC-157 as the intervention or exposure. Below are the review and the 3 individual studies.
Scores run from 1 to 5 and rate study design only. The rules and reason codes are on Study Scores. Each finding restates the abstract's own conclusion.
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| Score | Study | Design, n | Finding |
|---|---|---|---|
| 3 (SR +large -nonRCT) | Vasireddi, 2025 | Systematic review, 36 studies, n=12 | Adverse effects are possible due to unregulated manufacturing, contamination, or unknown clinical safety. We recommend that clinicians counsel athletes to understand their organizations' rules to remain compliant with... |
| Score | Study | Design, n | Finding |
|---|---|---|---|
| 1 (UNC) | Lee, 2025 | Uncontrolled human study, n=2 | Intravenous infusion of up to 20 mg of BPC-157 in 2 healthy adults showed no adverse effects and was well-tolerated. The results of this pilot study showed the safety of BPC-157 in humans. |
| 1 (UNC) | Lee, 2024 | Uncontrolled human study, n=12 | This is the first report of intravesical BPC-157 (10 mg) injection to help patients with moderate to severe interstitial cystitis who did not respond to pentosan polysulfate treatment. |
| 1 (UNC) | Lee, 2021 | Uncontrolled human study, n=17 | This small study suggests that intra-articular injection of BPC-157 helps with multiple types of knee pain. |